@Article{Zegarski2012,
journal="Gastroenterology Review/Przegląd Gastroenterologiczny",
issn="1895-5770",
volume="7",
number="4",
year="2012",
title="A study on the use of positron emission computed tomography analysis in recurrent colorectal cancer",
abstract=" Introduction:  Colorectal cancer is a common neoplasm in Europe and the United States. Even after apparently curative resection, recurrences occur in one-third of patients, usually within the first 2 to 3 years after the surgery.    Aim:  Investigation the role of 18-fluorodeoxyglucose positron emission tomography/computed tomography (18-FDG PET/CT) in detection of recurrent colorectal cancer.    Material and methods:  A retrospective analysis of 75 tumours from 59 patients with recurrent colorectal carcinoma was made.   Results:  Detecting recurrent colorectal cancer FDG PET/CT revealed 92% sensitivity. PET/CT correctly identified 69 of 75 tumours. Negative PET/CT results of the examination depend on necrotic changes occurring in them (p < 0.01). SUV max  in tumours without necrotic changes was indeed statistically higher than in tumours with necrotic changes (p < 0.01). SUV max  in tumours located in the liver is indeed statistically higher than in tumours located in lungs (p < 0.05). A correlation between SUV max  of the tumour and age of the patients and the maximum dimension of the tumour was not found   (p < 0.05).   Conclusions : This study demonstrates that PET/CT is of high sensitivity. We conclude that FDG PET/CT is a powerful diagnostic imaging method, which has ability to improve accurate detection of recurrent colorectal cancer. The limitations of PET/CT are related to cellularity of the tumours. It is necessary to continue the study on correlation between SUV and molecular factors of tumours.",
author="Zegarski, Wojciech
and Małkowski, Bogdan
and Śrutek, Ewa
and Klag, Michał
and Głowacka, Iwona",
pages="203--208",
doi="10.5114/pg.2012.30503",
url="http://dx.doi.org/10.5114/pg.2012.30503"
}