@Article{Pagni2012,
journal="Folia Neuropathologica",
issn="1641-4640",
volume="50",
number="3",
year="2012",
title="Case reportPrimary angiitis of the central nervous system: 2 atypical cases",
abstract=" The presence of an angiitis process in the central nervous system (CNS) characterizes different groups of conditions: from idiopathic pachymeningitis to lymphoproliferative disorders. In absence of specific infections, inflammatory and neoplastic diseases, the term “PACNS” (Primary Angiitis of the CNS) was proposed to indicate a peculiar vascular inflammation of unknown origin of meningeal vessels extending to the brain or spinal cord parenchyma. We report two cases of PACNS with peculiar and atypical features: the first one with a possible Epstein Barr Virus (EBV) relationship, the second one with spinal cord involvement only, treated surgically. We also hypothesize a correlation between EBV  chronic infection and possible subtypes of PACNS stressing the importance of EBER (EBV-encoded RNA) test in the routine examination of brain biopsies suspicious for PACNS. ",
author="Pagni, Fabio
and Isimbaldi, Giuseppe
and Vergani, Francesco
and Casiraghi, Paolo
and Marzorati, Laura
and Migliorino, Guglielmo
and Cattoretti, Giorgio",
pages="293--299",
doi="10.5114/fn.2012.30530",
url="http://dx.doi.org/10.5114/fn.2012.30530"
}