@Article{Akiyama2014,
journal="Journal of Contemporary Brachytherapy",
issn="1689-832X",
volume="6",
number="1",
year="2014",
title="Original paperHigh-dose-rate interstitial brachytherapy for mobile tongue cancer: preliminary results of a dose reduction trial",
abstract=" Purpose : To compare the outcome of our facility with another about the shortened schedule (60 Gy in 10 fractions to 54 Gy in 9 fractions) of high-dose-rate interstitial brachytherapy (HDR ISBT) for mobile tongue cancer.   Material and methods : Eighteen patients were treated with HDR ISBT as a monotherapy in dose reduction schedule with some unique technique to determine the border of tumor accuracy (lugol’s staining and metal marker), and to minimize adverse effect (lead-lined silicon block) at our facility.    Results:  The 2-year local and regional control rates and cause-specific survival rate were 82%, 80%, and 83% and moderate to severe late complications occurred in five patients (28%), which were almost the same treatment results achieved by another facility.   Conclusions : We recommend 54 Gy in 9 fractions over 7 days as a feasible treatment to reduce patient discomfort in mobile tongue cancer patients.",
author="Akiyama, Hironori
and Yoshida, Ken
and Yamazaki, Hideya
and Takenaka, Tadashi
and Kotsuma, Tadayuki
and Masui, Koji
and Yoshioka, Yasuo
and Arika, Takumi
and Shimizutani, Kimishige
and Tanaka, Eiichi",
pages="10--14",
doi="10.5114/jcb.2014.40726",
url="http://dx.doi.org/10.5114/jcb.2014.40726"
}