@Article{Ataş2014,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="13",
number="1",
year="2014",
title="Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography",
abstract=" Objective:  Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period.    Aim of the study : To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in postmenopausal women and compare with healthy reproductive-age women controls.    Material and methods:  The study population included a healthy reproductive-age control group (n = 72) and postmenopausal study group (n = 72). Retinal thickness parameters were measured by SD-OCT. Peripapillary RNFL thickness parameters, macular thickness and choroidal thickness were evaluated.   Results : Superior inner macula, temporal inner macula, inferior inner macula, nasal inner macula, inferior outer macula and choroid thickness were significantly thinner in the postmenopausal study group than the healthy reproductive-age control group (p = 0.007, p = 0.037, p = 0.027, p = 0.006, p = 0.016, p < 0.001, respectively). After adjusting for age, only choroid thickness was significantly thinner in the postmenopausal study group than controls (p† = 0.005).    Conclusions : This study revealed that choroidal thickness measured by SD-OCT was significantly thinner in postmenopausal women than healthy reproductive-age women. We can speculate that the decrease in choroidal thickness in postmenopausal women may indicate a reduced estrogen-dependent vasodilatory effect in ophthalmic artery secondary to menopausal estrogen deficiency.",
author="Ataş, Mustafa
and Açmaz, Gökhan
and Aksoy, Hüseyin
and Demircan, Süleyman
and Göktaş, Altan
and Arifoğlu, Hasan Basri
and Zararsız, Gökmen",
pages="36--41",
doi="10.5114/pm.2014.41088",
url="http://dx.doi.org/10.5114/pm.2014.41088"
}