@Article{Kochman2014,
journal="Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej",
issn="1734-9338",
volume="10",
number="4",
year="2014",
title="Original paperDirect transcatheter aortic valve implantation – one-year outcome of a case control study",
abstract=" Introduction : Transaortic valve implantation (TAVI) has a well-established position in the treatment of high-risk and inoperable patients with severe aortic stenosis (AS). The TAVI protocol requires a pre-dilatation for native valve preparation.    Aim : To assess the safety and feasibility of TAVI without pre-dilatation and to compare it with the procedure with pre-dilatation.   Material and methods:  Out of 101 TAVI patients, in 10 the procedure was performed without balloon predilatation, and 8 patients were included in the analysis. The procedural, echocardiographic, and clinical outcomes were compared with a case control matched cohort (1 : 2 ratio). A 12-month follow-up was done in all cases.    Results:  The procedure was successfully completed in all patients in the study group (SG), but there was one procedural failure in the control group (CG). All patients received a CoreValve (Medtronic) bioprosthesis. There was a significant immediate decrease in transvalvular gradients (TG) in both study arms after the procedure (SG: mean TG: from 46.0 ±14.0 mm Hg to 10.0 ±4.8 mm Hg, p < 0.001; CG: mean TG: from 55.9 ±12.0 mm Hg to 9.9 ±2.9 mm Hg, p < 0.001). A marked increase in the effective orifice areas was observed in both cohorts (SG: 1.63 ±0.13 cm 2  and CG: 1.67 ±0.25 cm 2 , p = 0.75). The periprocedural complication rate was equally distributed in both arms. The 12-month all-cause mortality was 12.5% in both groups.    Conclusions : The direct TAVI approach seams to be safe and feasible. The clinical and echocardiographic results are not different from those achieved in patients treated with standard TAVI protocol with pre-dilatation.",
author="Kochman, Janusz
and Kołtowski, Łukasz
and Huczek, Zenon
and Scisło, Piotr
and Bakoń, Leopold
and Wilimski, Radosław
and Rymuza, Bartosz
and Opolski, Grzegorz",
pages="250--257",
doi="10.5114/pwki.2014.46766",
url="http://dx.doi.org/10.5114/pwki.2014.46766"
}