@Article{Serin2015,
journal="Gastroenterology Review/Przegląd Gastroenterologiczny",
issn="1895-5770",
volume="10",
number="3",
year="2015",
title="The prevalence of Helicobacter pylori infection in patients with gastric and duodenal ulcers – 
a 10-year, single-centre experience",
abstract=" Introduction :  Helicobacter pylori  ( H. pylori ) occurs throughout the world and causes gastroduodenal diseases. There is data indicating a change in the prevalence of  H. pylori  infection worldwide. The prevalence of  H. pylori  is 80% in Turkey, while it is higher in many developing countries, and the rate of infection varies throughout the world. In many developing countries, the prevalence of infection exceeds 90% by adulthood.   Aim : To determine the change in the rate of  H. pylori  infection in gastric ulcers and duodenal ulcers for a 10-year period in a single centre.   Material and methods : The study population included 550 patients (342 in 2004, 208 in 1994) with gastric and duodenal ulcers.   Results : In 2004 there were 125 (36.5%) patients with gastric ulcer and 217 patients with duodenal ulcer (64.5%). CLO test positivity was 39.2% in patients with gastric ulcers and 60% in patients with duodenal ulcers. In 1994 there were 208 patients (159 duodenal ulcers, 49 gastric ulcers). Urease test was positive in 74.2% of patients with duodenal ulcer and in 65.2% of patients with gastric ulcer. The decrease in the rate of urease positivity in patients with gastric ulcer was statistically significant (p = 0.01) during this 10-year period.   Conclusions : In the present study we found that the urease positivity decreased significantly in patients with gastric ulcer between 1994 and 2004.",
author="Serin, Ayfer
and Tankurt, Ethem
and Şarkış, Cihat
and Simsek, Ilkay",
pages="160--163",
doi="10.5114/pg.2015.49685",
url="http://dx.doi.org/10.5114/pg.2015.49685"
}