@Article{Emiroglu2015,
journal="Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii",
issn="1642-395X",
volume="32",
number="5",
year="2015",
title="Serum IL-17A in Behçet’s disease",
abstract=" Introduction : Behçet’s disease is a chronic multisystem disease with spontaneous remissions and relapses. Several studies show that autoimmune mechanisms play an important role in the development of Behçet’s disease. Activation of T cells and neutrophils is important in the pathogenesis of the disease. Interleukin 17 (IL-17) is a new cytokine that induces several types of cells to secrete proinflammatory cytokines in many inflammatory and autoimmune diseases.   Aim : This study evaluated the serum levels of IL-17A in active and stable Behçet’s disease patients.   Material and methods : Seventy-six patients who had active clinic findings of Behçet’s disease were enrolled in our study. Seventy age- and sex-matched controls were also enrolled. Serum IL-17 levels were studied in peripheral venous blood samples.   Results : No significant differences were found between active Behçet’s disease patients and controls in terms  of serum IL-17A (p > 0.05).   Conclusions : These results suggest that IL-17A serum levels do not play an important role in active Behçet’s disease.",
author="Emiroglu, Nazan
and Cengiz, Fatma Pelin
and Erdem, Gul Bahar",
pages="358--361",
doi="10.5114/pdia.2015.54745",
url="http://dx.doi.org/10.5114/pdia.2015.54745"
}