@Article{Ishiyama2016,
journal="Journal of Contemporary Brachytherapy",
issn="1689-832X",
volume="8",
number="1",
year="2016",
title="Dosimetry of permanent interstitial prostate brachytherapy for an intraoperative procedure, using O-arm based CT and TRUS",
abstract=" Purpose:  The aim of this report is dosimetric evaluation for an intraoperative fusion computed tomography (CT) as a superior predictor of 1-month CT based dosimetry in comparison to transrectal ultrasound (TRUS) in permanent interstitial prostate brachytherapy.    Material and methods : Data of 65 patients treated with seed implantation were analyzed. All procedures has been performed with patients in the lithotomy position inside the O-arm system. An end-fine probe is used as a landmark to fuse TRUS and O-arm-based CT images. There was no difference in the patient’s position, probe position, and timing of image acquisition between the two imaging modalities. Dose-volume histogram (DVH) parameters such as the dose to 90% of prostate volume (D 90 ) has been analyzed.    Results:   The area under the curve of the receiver operating characteristic tended to be larger on fusion CT than on TRUS for most DVH parameters (71.85% vs. 59.59% for D 90 ; p = 0.07). Significant relationships between fusion CT and 1-month CT were confirmed using Pearson’s correlation coefficients for most DVH parameters (R = 0.48, p < 0.01 for D 90 ), although the relationship between TRUS and 1-month CT was poor. Large dose reduction (35 Gy for D 90 ) was seen from TRUS to fusion CT, especially in patients with high body weight and small prostate volume.    Conclusions : Intraoperative fusion CT appears to have higher predictive power for 1-month CT-based dosimetry than TRUS. A prospective trial using fusion CT-based planning is warranted.",
author="Ishiyama, Hiromichi
and Sekiguchi, Akane
and Satoh, Takefumi
and Tsumura, Hideyasu
and Takenaka, Kouji
and Kawakami, Shogo
and Tabata, Ken-ichi
and Kobayashi, Kentaro
and Iwamura, Masatsugu
and Hayakawa, Kazushige",
pages="7--16",
doi="10.5114/jcb.2016.57817",
url="http://dx.doi.org/10.5114/jcb.2016.57817"
}