@Article{Algiert2016,
journal="Dermatology Review/Przegląd Dermatologiczny",
issn="0033-2526",
volume="103",
number="6",
year="2016",
title="Low frequency of skin cancers in vitiligo patients",
abstract="Vitiligo is a disease characterized by discoloration of the skin and hair as a result of damage of melanocytes. The exact mechanism of the disease is still unknown. Theories about the pathogenesis focus on autoimmune, neurogenic and autocytotoxic mechanisms. There is a decreased risk of incidence of skin cancers in patients with vitiligo. The relation between vitiligo and decreased frequency of cases of malignant melanoma (MM) may be a consequence of the immune response to antigens, which are common for melanocytes and MM cells. Genetic studies indicate a mutually exclusive relationship of melanoma and vitiligo. This disease is also associated with a polymorphism in the TYR gene which encodes tyrosinase. Studies also indicate a decreased risk of incidence of nonmelanoma skin cancers (NMSC) in patients with vitiligo.",
author="Algiert, Barbara
and Erkiert-Polguj, Anna
and Dana, Agnieszka
and Czubiński, Dariusz
and Rotsztejn, Helena",
pages="486--490",
doi="10.5114/dr.2016.63840",
url="http://dx.doi.org/10.5114/dr.2016.63840"
}