@Article{Gudowska2016,
journal="Clinical and Experimental Hepatology",
issn="2392-1099",
volume="2",
number="4",
year="2016",
title="Simple non-invasive markers for early diagnosis and determination of the severity of liver diseases",
abstract=" Aim of the study : The aim of the study was to evaluate the effect and severity of liver diseases of different etiologies on the values of three non-invasive fibrosis markers.    Material and methods : Serum samples from 65 patients with alcoholic cirrhosis, 31 with non-alcoholic cirrhosis and 32 with toxic hepatitis, were tested. Cirrhotic patients were classified according to the Child-Pugh scale. The age-platelet (AP) index, HUI score and Fibro Q index were calculated using the specific formulas.    Results:  The values of all tested scores were significantly higher in controls than in patients with liver diseases and were significantly different between liver diseases. The patients with alcoholic and non-alcoholic cirrhosis had higher values of the AP index, HUI score and Fibro Q index than patients with toxic hepatitis. HUI and Fibro Q scores appeared to vary according to the severity of liver damage and were higher in Child-Pugh class C than in classes A and B.   Conclusions : We conclude that all tested scores based on liver function tests are good markers for non-invasive diagnosis of liver damage. Additionally, HUI and Fibro Q scores reflect the severity of liver cirrhosis.",
author="Gudowska, Monika
and Wrona, Alicja
and Gruszewska, Ewa
and Panasiuk, Anatol
and Cylwik, Bogdan
and Swiderska, Magdalena
and Filisiak, Robert
and Szmitkowski, Maciej
and Chrostek, Lech",
pages="149--154",
doi="10.5114/ceh.2016.63872",
url="http://dx.doi.org/10.5114/ceh.2016.63872"
}