@Article{Bura2017,
journal="Family Medicine \& Primary Care Review",
issn="1734-3402",
volume="19",
number="1",
year="2017",
title="Moderate and severe pharyngitis in young adult inhabitants of Poznan, western Poland",
abstract=" Background.   Acute pharyngitis is a frequent clinical problem.   Objectives.   To assess: the frequency of streptococcal etiology (β-HS ) in moderate to severe pharyngitis among young adult patients, the accuracy of the Centor score (CS ) in predicting the likelihood of the β-HS etiology and the usefulness of the rapid antigen detection test (RAD T) in the appropriate selection of patients that ought to be treated with antibiotics.   Material and methods . 202 individuals (101 patients and a sex- and age-matched control group) aged 18–44 participated in the study. Two throat swabs were performed: the first one to carry out RAD T for group A streptococci (GAS ), and the second one to grow a conventional culture. Data on the antibiotic therapy were recorded as well.   Results.   β-HS were responsible for one-third of the studied cases of pharyngitis (GAS – 22.8%, 23/101; high non-GAS colony count – 9.9%, 10/101). The frequency of the isolation of β-HS depending upon the CS was as follows: CS 2 – 13.2% (5/36), CS 3 – 40.5% (15/36), CS 4 – 61.5% (16/36). RAD T’s effectiveness in identifying GAS was significantly higher than that of CS alone (p < 0.001). Antibiotics were prescribed in 59 cases, including 45% of RAD T-negative patients (35/77). The primary choice was penicillin (37.3%, 22/59).   Conclusions . In young adult pharyngitis patients with CS 2-4, β-HS are responsible for a minority of cases. Among these bacteria, almost one third are non-GAS . Centor criteria, as the only diagnostic tool in predicting the streptococcal etiology of the disease, are of moderate usefulness. The use of RAD T significantly increases the diagnostic accuracy of GAS –related pharyngitis.",
author="Bura, Maciej
and Michalak, Michał
and Chojnicki, Michał
and Padzik, Magdalena
and Mozer-Lisewska, Iwona",
pages="12--17",
doi="10.5114/fmpcr.2017.65084",
url="http://dx.doi.org/10.5114/fmpcr.2017.65084"
}