@Article{Olejek2005,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="4",
number="1",
year="2005",
title="Photodynamic diagnosis and therapy of epithelial vulvar diseases",
abstract="Photodynamic method is a new technique with unique properties that make it attractive for treatment of vulvar epithelial disorders. Authors describe photodynamic method in their own studies: diagnosis and treatment of lichen sclerosus and diagnosis of vulvar intraepithelial neoplasia and condylomata accuminata vulvae. 42 patients were treated with histopathological diagnosis of lichen sclerosus. 2., 5 hours after topical application of 20% 5-ALA, photodynamic diagnosis was conduced. Afterwards all the areas were irradiated with semiconductor laser, energy dose 120 J/cm 2 , fluence rate 400 mW/cm 2 . Patients underwent 3-6 cycles PDT in 2 weeks intervals. 2-4 weeks after last therapy patients underwent clinical, photodynamic and histopathological verification. 14 patients with VIN had 10% ALA applied to the entire vulva. 1 hour after drug application the vulva was examinated in white light and in fluorescence light at a wavelength of 442 nm. Next, 13 patients were treated by surgical excision and the histopathological character of the resected tissues was established.   Photodynamic method using 5-ALA represents an alternative treatment method for lichen sclerosus and has the advantage of minimal tissue destruction, low side effects and excellent cosmetic results.",
author="Olejek, Anita
and Rembielak-Stawecka, Beata
and Kozak-Darmas, Iwona",
pages="20--22",
url="https://www.termedia.pl/Photodynamic-diagnosis-and-therapy-of-epithelial-vulvar-diseases,4,2951,1,1.html"
}