@Article{Żychowska2017,
journal="Dermatology Review/Przegląd Dermatologiczny",
issn="0033-2526",
volume="104",
number="2",
year="2017",
title="Chronic graft-versus-host disease – the role of dermatological treatment",
abstract=" Introduction . The number of allogeneic haematopoietic stem cell transplantations is increasing year by year. The most common long-term complication is chronic graft-versus-host disease, with skin involvement noted in over 90% of cases.    Objective . To present and discuss skin lesions occurring in chronic graft-versus-host disease with a particular focus on available dermatological treatment modalities.   Case report . A 45-year-old male patient, who received allogeneic haematopoietic stem cell transplantations in December 2012, presented for the treatment of skin lesions secondary to chronic graft-versus-host disease. Clinical examination revealed hyperpigmented lichenoid eruption on the trunk; irregular patches of non-scarring alopecia; poikiloderma on the face and upper limbs; and sclerodermatous lesions on the hands with diffuse epidermal exfoliation on the palms and soles. Histopathological examination confirmed the diagnosis of chronic graft-versus-host disease. Treatment consisting of phototherapy and intensive topical treatment was introduced.   Conclusions . Skin lesions secondary to chronic graft-versus-host disease may impair the daily functioning of post-transplant patients. Comprehensive therapeutic management should be based on the cooperation between haematologists and dermatologists.",
author="Żychowska, Magdalena
and Gruber-Kopczyńska, Joanna
and Tupikowska-Marzec, Małgorzata
and Maj, Joanna",
pages="112--121",
doi="10.5114/dr.2017.67385",
url="http://dx.doi.org/10.5114/dr.2017.67385"
}