@Article{Malukiewicz2016,
journal="Klinika Oczna / Acta Ophthalmologica Polonica",
issn="0023-2157",
volume="118",
number="1",
year="2016",
title="Use of nonsteroidal anti-inflammatory drugs in diabetic retinopathy",
abstract=" Introduction : Diabetic macular edema, a manifestation of diabetic retinopathy, occurs more frequently in type 2 diabetes mellitus. There is evidence that inflammation plays a prominent role in the pathogenesis. A number of pro-inflammatory cytokines are consistently elevated in the vitreous of patients with advanced stages of diabetic retinopathy. Nonsteroidal anti-inflammatory drugs inhibit the catalytic activity of the cyclooxygenase isoenzymes COX-1 and COX-2, the key enzymes in inflammatory processes.  	 Purpose : To present current knowledge of benefits and limitations of using nonsteroidal anti-inflammatory drugs in diabetic retinopathy.  	 Conclusions : Nonsteroidal anti-inflammatory drugs may be considered as an adjuvant treatment in diabetic retinopathy especially in patients with diabetic macular edema.",
author="Malukiewicz, Grażyna
and Stafiej, Joanna
and Lesiewska, Hanna
and Sikorski, Bartosz",
pages="44--47",
doi="10.5114/ko.2016.71655",
url="http://dx.doi.org/10.5114/ko.2016.71655"
}