@Article{Grewling2018,
journal="Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii",
issn="1642-395X",
volume="35",
number="1",
year="2018",
title="Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia",
abstract=" Introduction : The role of long-distance transported (LDT)  Ambrosia  pollen in inducing new sensitization and affecting sensitization rates in  Artemisia -sensitized patients is unclear.    Aim : The aim of this study was to estimate the degree of cross-sensitization to  Ambrosia / Artemisia  allergens in citizens of Poznan (Western Poland). This area is covered by extensive  Artemisia  populations but does not currently have local  Ambrosia  populations.   Material and methods : Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of  Artemisia  vulgaris and  Ambrosia   artemisiifolia , an allergenic component of  A. vulgaris  (nArt v 1), and an allergenic component of A.  artemisiifolia  ( nAmb a 1 ). Skin prick tests (SPTs, n = 86) were performed with pollen allergen extracts of  A. vulgaris  and A.  artemisiifolia .  Artemisia  and  Ambrosia  pollen in ambient air was collected (1996–2013) by a Hirst type volumetric trap sited at roof level (33 m).    Results : The SPT showed that the prevalence of sensitization to  Ambrosia  and  Artemisia  pollen exceeded 3.5%, and 10.5%, respectively. The measurements of IgE in blood serum (CAP-FEIA) revealed that among  Ambrosia -sensitized patients 90.1% (20/22 patients) were concomitantly sensitized to  Artemisia . 59.1% (13/22) of these patients reacted to nArt v 1, suggesting primary sensitization to  Artemisia  pollen. Only 2 (9.1%) patients were mono-sensitized to  Ambrosia  pollen extract, but surprisingly not to  nAmb a 1 .    Conclusions : The LDT  Ambrosia  pollen had a negligible effect on the rate of sensitization to  Ambrosia  allergens in Poznan and did not increase the prevalence of sensitization to  Artemisia  pollen in this region. However, the majority of patients showing hypersensitization to  Artemisia  pollen might also present symptoms during elevated episodes of LDT of  Ambrosia  pollen.",
author="Grewling, Łukasz
and Jenerowicz, Dorota
and Bogawski, Paweł
and Smith, Matt
and Nowak, Małgorzata
and Frątczak, Agata
and Czarnecka-Operacz, Magdalena",
pages="83--89",
doi="10.5114/ada.2018.73167",
url="http://dx.doi.org/10.5114/ada.2018.73167"
}