@Article{Benej2017,
journal="Polish Journal of Pathology",
issn="1233-9687",
volume="68",
number="4",
year="2017",
title="Soft tissue metastasis of mediastinal non-functioning paraganglioma with unusual TTF-1 expression: a potential diagnostic pitfall",
abstract="Metastatic extra-adrenal paragangliomas are very rare and can represent diagnostic challenges. We report a case of 69-year-old man with a tumor of the right shoulder. Histologic and immunohistochemical examinations confirmed the diagnosis of paraganglioma. Surprisingly, tumor cells were diffusely thyroid transcription factor 1 (TTF-1) positive. Succinate dehydrogenase complex subunit B (SDHB) deficiency has not been detected. Inherited syndromes associated with paragangliomas were ruled out. The primary tumor was identified in the mediastinum. This is the first report of TTF-1 expression in paraganglioma. To avoid misdiagnosis, careful clinical and pathological examination of any tumor with organoid growths pattern is necessary.",
author="Benej, Michal
and Zambo, Iva
and Bílek, Ondrej
and Capov, Ivan",
pages="354--358",
doi="10.5114/pjp.2017.73931",
url="http://dx.doi.org/10.5114/pjp.2017.73931"
}