@Article{Bręborowicz2005,
journal="Archives of Medical Science",
issn="1734-1922",
volume="1",
number="1",
year="2005",
title="ORIGINAL PAPERThe effect of hormone replacement therapy on the left ventricle systolic and diastolic function in postmenopausal women with coronary artery disease",
abstract=" Introduction:  The aim of this study was to evaluate the effect of hormone replacement therapy (HRT) on the left ventricle systolic and diastolic function.  Materials and methods: Fifty-six postmenopausal women with proven coronary artery disease (CAD) were enrolled into the study (31 were assigned to HRT and 25 were matched as a control group). Clinically both groups were comparable. All patients had standard 2D and Doppler echocardiography study at the baseline and after 12 months of follow up.   Results:  The heart geometry and wall thickness did not change significantly in both groups and were comparable after 12-months of follow-up: EDD: 45.6\±6.0 to 44.6\±8.1 vs. 47.8\±7.1 to 47.2\±4.4; ESD: 29.5\±7.1 to 29\±8.8 vs. 34.3\±6.7 to 34.4\±7.7; RV: 21.9\±6.1 to 23.1\±7 vs. 21.5\±5.8 to 21.8\±3.2; LA: 32\±4.7 to 35.6\±7.9 vs. 34.3\±4.2 to 34\±4.4; Ao: 28.8\±3.3 to 29.2\±4.5 vs. 28.8\±2.2 to 28.5\±3.4; IVS: 9.9\±1.4 to 10\±1 vs. 10\±1.3 to 10.3\±1.6; PW: 10.2\±1.1 to 10\±1 vs. 10.1\±1.6 to 10.3\±1.4. Left ventricle systolic and diastolic parameters did not change significantly in both groups and were comparable after 12-months of follow-up: LVEF (%): 64.3\±13.4 to 68.4\±14.9 vs. 56.6\±12.5 to 59.9\±13; ESV (ml): 35.3\±39.8 to 40.4\±57.2 vs. 42.9\±23.9 to 38.6\±16.4; IVRT (ms): 120.9\±22.8 to 112.2\±15.4 to 112.8\±27.7 to 109.3\±12.8; E: A: 1.17\±1.17 to 1\±0.48 vs. 0.97\±0.41 to 0.94\±0.35; DCT (E) (ms): 152.4\±70.6 to 150.2\±50.9 vs. 149.3\±69.1 to 176.8\±61.4; EDV (ml): 84.9\±62.6 to 98.3\±69.7 vs. 96.9\±43.6 to 96.1\±26.9.   Conclusions:  Short term transdermal HRT has no effect on the left ventricle systolic and diastolic function in women with CAD.",
author="Bręborowicz, Piotr
and Mularek-Kubzdela, Tatiana
and Oko-Sarnowska, Zofia
and Trojnarska, Olga
and Maciejewska, Marzena
and Bręborowicz, Elżbieta
and Warenik-Szymankiewicz, Alina
and Cieśliński, Andrzej",
pages="18--22",
url="https://www.termedia.pl/ORIGINAL-PAPER-The-effect-of-hormone-replacement-therapy-on-the-left-ventricle-systolic-and-diastolic-function-in-postmenopausal-women-with-coronary-artery-disease,19,3227,1,1.html"
}