@Article{Adamczyk2018,
journal="Dermatology Review/Przegląd Dermatologiczny",
issn="0033-2526",
volume="105",
number="3",
year="2018",
title="Efficacy and safety of agents containing betamethasone dipropionate and calcipotriol in topical therapy of psoriasis",
abstract="Glucocorticosteroids and vitamin D analogues are the most widely used topical agents in the treatment of psoriasis. Betamethasone dipropionate and calcipotriol in fixed-dose combination act synergistically on the pathogenesis of psoriasis, exerting both, anti-inflammatory, immunomodulatory and anti-proliferative effects. Two-compound products are the most effective drugs among all topical anti-psoriasis agents; they are also very convenient in everyday use and well tolerated. For this reasons the Polish Dermatological Society recommends this agents as first-line treatment option in patients with scalp, glabrous skin and  palmo-plantar psoriasis. Data from clinical trials provide evidence about safety and effectiveness of these two-compound products in long-term psoriasis management. Recently, a new formulation was marketed – a fixed-dose foam, which acts even stronger than previous products. In this review we present data justifying the use of betamethasone dipropionate/calcipotriol agents in the treatment of psoriasis, emphasizing their mode of action, efficacy and safety.",
author="Adamczyk, Michał
and Bartosińska, Joanna
and Krasowska, Dorota",
pages="434--450",
doi="10.5114/dr.2018.77113",
url="http://dx.doi.org/10.5114/dr.2018.77113"
}