@Article{Tomik2005,
journal="Folia Neuropathologica",
issn="1641-4640",
volume="43",
number="2",
year="2005",
title="Original articleDoes apoptosis occur in amyotrophic lateral sclerosis? TUNEL experience from human Amyotrophic Lateral Sclerosis (ALS) tissues",
abstract="The role that apoptosis plays in the pathogenesis of amyotrophic lateral sclerosis (ALS) is still unclear. From our autopsy samples, we have undertaken an effort to verify if apoptosis in ALS really occurs or if can at least be detected. The study was performed using TUNEL method for screening the apoptotic changes in the autopsy samples from 8 ALS cases compared with 16 control cases. No features of apoptosis (DNA cleavages) were noted in any of the investigated regions of the central nervous system in ALS cases as well as in controls. These preliminary results seem to support the reports, which deny the role of apoptosis in human ALS. The following investigations using additional methods will be performed for detection the apoptotic signals in ALS.",
author="Tomik, Barbara
and Adamek, Dariusz
and Pierzchalski, Piotr
and Banares, Steven
and Duda, Aleksandra
and Partyka, Dorota
and Pawlik, Wiesław
and Kałuża, Józef
and Krajewski, Stan
and Szczudlik, Andrzej",
pages="75--80",
url="https://www.termedia.pl/Original-article-Does-apoptosis-occur-in-amyotrophic-lateral-sclerosis-TUNEL-experience-from-human-Amyotrophic-Lateral-Sclerosis-ALS-tissues,20,3428,1,1.html"
}