@Article{Mess2019,
journal="Medycyna Paliatywna/Palliative Medicine",
issn="2081-0016",
volume="11",
number="1",
year="2019",
title="A new look on vitamin D – role in oncological disorders",
abstract="Molecules from vitamin D group belong to organic, lipid-soluble substances classifed as secosteroids which are characterized by cleavage of the B ring of the core structure. Vitamin D receptors are localized on cells in many different types of tissues and organs which makes vitamin D has pleiotropic functions and influences on functioning of whole body and modifies course of different diseases. Calcitriol affects the biology of cells with two different pathways: genomic and non-genomic actions. Results of many surveys suggest the correlation between vitamin D concentration and risk of many different tumors. Vitamin D deficiency can play role in breast cancer, prostate cancer, colorectal cancer or malignant melanoma. Furthermore, vitamin D is crucial for calcium and phosphate homeostasis and it’s deficiency may cause musculoskeletal, cardiovascular and respiratory disorders.",
author="Mess, Eleonora
and Pająk, Wiktoria
and Ornat, Maciej",
pages="21--26",
doi="10.5114/pm.2019.83841",
url="http://dx.doi.org/10.5114/pm.2019.83841"
}