@Article{Panek2005,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="4",
number="4",
year="2005",
title="The case of using antiangiogenic agent \– plasmide vector psFLT and radiochemotherapy in locally advanced vulvar cancer",
abstract="This is a case report documenting a successful use of antiangiogenic agent- plasmide vector psFLT with successive chemo-radiotherapy and radical surgery in patient with primarily unoperable invasive carcinoma of the vulva.  After 3 courses of subcutaneous injection of 30 micrograms of Plasmide vector psFLTa significant reduction of the tumor size was obtained.  Subsequently chemo-irradiation was 5-Fluorouracil and Mitomycin-C was carried out resulting in complete clinical regression of the tumor. Radical vulvectomy and inguino-femoral limphadenectomy was performed 6 weeks after completion of chemo-irradiation. Microscopic examination of the specimen revealed a complete eradication of the malignant tissue.  The case demonstrates a significant potential of antiangiogenic therapy combiened with chemo-irradiation for locally advanced carcinoma of the vulva. This experimental method of treatment deserves further investigation.",
author="Panek, Grzegorz
and Gawrychowski, Krzysztof
and Bidziński, Mariusz
and Krynicki, Ryszard
and Małecki, Maciej",
pages="17--21",
url="https://www.termedia.pl/The-case-of-using-antiangiogenic-agent-8211-plasmide-vector-psFLT-and-radiochemotherapy-in-locally-advanced-vulvar-cancer,4,3635,1,1.html"
}