@Article{Cserni2019,
journal="Polish Journal of Pathology",
issn="1233-9687",
volume="70",
number="2",
year="2019",
title="Spontaneous pathological complete regression of high-grade triple-negative breast cancer with axillary metastasis",
abstract="We report on a breast carcinoma with medullary features diagnosed by core needle biopsy in a 72-year-old woman. Both the primary tumour and its fine needle aspiration-proven, rapidly growing axillary metastasis regressed completely in less than 2 months, by the time surgery was performed. The biopsy of the primary tumour demonstrated a dense stromal infiltrate of CD8+/granzyme B+ activated cytotoxic T-cells suggestive of a robust antitumour immune response. Paradoxically, both tumour cells and tumour infiltrating immune cells demonstrated a diffuse PD-L1 expression, revealing that antitumour immune response has the ability to spontaneously overcome inhibitory mechanisms induced by cancerous growth.",
author="Cserni, Gábor
and Serfozo, Orsolya
and Ambrózay, Éva
and Markó, László
and Krenács, László",
pages="139--143",
doi="10.5114/pjp.2019.87105",
url="http://dx.doi.org/10.5114/pjp.2019.87105"
}