@Article{Olesińska2005,
journal="Reumatologia/Rheumatology",
issn="0034-6233",
volume="43",
number="5",
year="2005",
title="REVIEW PAPERAnti-ribosomal P protein antibodies: clinical significance and role in pathogenesis of systemic lupus erythematosus",
abstract="Ribosomal P protein is a pentamere composed of 3 phosphoproteins: P0, P1 and P2 with molecular weights, respectively: 38, 19 i 17 kDa.  Their function is not exactly known, it is supposed that are essential for all 3 stages of protein synthesis and for regulation of ribosomal GTP activity.  Anti-P antibodies react to at least 1 epitope common to all 3 proteins and corresponding to a single sequential antigenic determinant present in the carboxyl-terminal 22-amino-acid sequence. ELISA and immunoblotting are used in detection of anti-P antibodies.  There is a wide variation in the reported prevalence of these antibodies in SLE patients. Some authors found it in 5-10% but the others revealed anti-P in 42% of SLE patients.  It has been reported that anti-ribosomal P antibodies correlate with high activity SLE, risk of CNS or renal involvement and hepatic or haematologic complications.",
author="Olesińska, Marzena",
pages="274--279",
url="https://www.termedia.pl/REVIEW-PAPER-Anti-ribosomal-P-protein-antibodies-clinical-significance-and-role-in-pathogenesis-of-systemic-lupus-erythematosus,18,3892,1,1.html"
}