@Article{Hernandez Baltazar2020,
journal="Folia Neuropathologica",
issn="1641-4640",
volume="58",
number="2",
year="2020",
title="Does lipopolysaccharide-based neuroinflammation induce microglia polarization?",
abstract="Lipopolysaccharide (LPS) is a potent immunogen when administered locally and/or systemically. The peripheral immunization with LPS could contribute to the progression of neurological diseases because a strong link between neuroinflammation and dopaminergic degeneration has been found. The switch between the survival and neuronal death in substantia nigra could be related to M1 (neurotoxic) and M2 (neuroprotective) microglia phenotypes. In this review, we present the current findings about microglia roles, biomarkers, and natural or synthetic immune modulators determined in the LPS-based murine model.",
author="Hernandez Baltazar, Daniel
and Nadella, Rasajna
and Barrientos Bonilla, Abril
and Flores Martínez, Yazmin
and Olguín, Abraham
and Heman Bozadas, Paola
and Rovirosa Hernández, María
and Cibrián Llanderal, Iliana",
pages="113--122",
doi="10.5114/fn.2020.96755",
url="http://dx.doi.org/10.5114/fn.2020.96755"
}