@Article{Szczerkowska-Dobosz2020,
journal="Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii",
issn="1642-395X",
volume="37",
number="5",
year="2020",
title="Pathogenesis of psoriasis in the “omic” era. Part IV.
Epidemiology, genetics, immunopathogenesis, clinical
manifestation and treatment of psoriatic arthritis",
abstract="Psoriatic arthritis (PsA) is a chronic, progressive, inflammatory arthropathy associated with psoriasis as well as a complex pathogenesis. Genetic and environmental factors trigger the development of the immune-mediated auto-inflammatory response in different sites: skin, bone marrow, entheses and synovial tissues. Studies of the last two decades have changed the view of PsA from a mild, non-progressive arthritis to an inflammatory systemic disease with serious health consequences, not only associated with joint dysfunction, but also with an increased risk of cardiovascular disease and socioeconomic consequences with significantly reduced quality of life. The joint damage starts early in the course of the disease, thus early recognition and treatment with modern biological treatments, which may modify the natural history and slow down progression of this debilitating disease, is essential for the patient long-term outcome.",
author="Szczerkowska-Dobosz, Aneta
and Krasowska, Dorota
and Bartosińska, Joanna
and Stawczyk-Macieja, Marta
and Walczak, Aleksandra
and Owczarczyk-Saczonek, Agnieszka
and Reich, Adam
and Batycka-Baran, Aleksandra
and Czajkowski, Rafał
and Dobrucki, Iwona
and Dobrucki, Lawrence
and Górecka-Sokołowska, Magdalena
and Janaszak-Jasiecka, Anna
and Kalinowski, Leszek
and Nowicki, Roman
and Płoska, Agata
and Purzycka-Bohdan, Dorota
and Radulska, Adrianna
and Reszka, Edyta
and Samotij, Dominik
and Siekierzycka, Anna
and Slominski, Andrzej T.
and Slominski, Radomir M.
and Sobalska-Kwapis, Marta
and Strapagiel, Dominik
and Szczęch, Justyna
and Żmijewski, Michał
and Nedoszytko, Bogusław",
pages="625--634",
doi="10.5114/ada.2020.100478",
url="http://dx.doi.org/10.5114/ada.2020.100478"
}