@Article{Stoczynska-Fidelus2022,
journal="Alergologia Polska - Polish Journal of Allergology",
issn="2353-3854",
volume="9",
number="2",
year="2022",
title="The concept of a false-positive (result) in the context of COVID-19 diagnostics and medical recommendations",
abstract="COVID-19 is an example of a big challenge for diagnostics. In the case of many diseases and syndromes, there is a possibility to repeat the tests, and the time allocated for diagnosis is counted even in weeks, not in hours, as in COVID-19. The situation related to COVID-19, therefore leads to a large number of tensions, both among diagnostic physicians and patients. Especially that in this case, based on a positive result, the decision is being made not only about the choice of a possible therapy, but also about quarantine. This article refers to the predictive value of tests used in the diagnosis of COVID-19 (mainly RT-PCR), focusing on the concept of a false positive result. The article demonstrates that this is a relative term, depending on the question posed, the purpose of the diagnosis (selection of therapy, quarantine decision, disease detection), or even the variant of the SARS-CoV-2 virus. Effective vaccination against COVID-19, the increasing percentage of convalescent patients, and the emergence of the SARS-CoV-2 omicron variant minimalize all these problems. However, shifting away from widely used screening tests, should not cause abandoning COVID-19 testing completely.  Part of the population may still die from the disease and effective targeted therapy already exists. In order to personalize this therapy, a test such as RT-PCR must be used.",
author="Stoczynska-Fidelus, Ewelina
and Rieske, Piotr",
pages="78--88",
doi="10.5114/pja.2022.116289",
url="http://dx.doi.org/10.5114/pja.2022.116289"
}