@Article{Lakimenko2010,
journal="Klinika Oczna / Acta Ophthalmologica Polonica",
issn="0023-2157",
volume="112",
number="3",
year="2010",
title="Treatment of post-burn persistent corneal 
ulcers with excimer laser phototherapeutic 
keratectomy. Prospective clinical trial",
abstract="Purpose: To evaluate efficacy of excimer laser phototherapeutic keratectomy (PTK) in treatment of patients with post-burn persistent corneal ulcers.  Material and methods: Study design – nonrandomized trial with a “historic” control group. 54 eyes (53 patient) with central superficial post-burn corneal ulcers that were formed in different time frame (18-104 days) after grade IV burns were included into   the study. Among these 26 patients (26 eyes) were included prospectively – they underwent 1-time PTK. Control group consists of 27 patients (28 eyes), who underwent surgical keratectomy of ulcer edge and base. Indication for surgery in both groups   was non-decreasing size of ulcer during 7-14 days of conventional treatment. Patients of both groups wore therapeutic contact   lenses after surgery. Outcome measures were number of cases of corneal healing, number of complications, terms of corneal   epithelialization, visual acuity.  Results: PTK promoted corneal healing in 24/26 patients, surgical keratectomy was effective in 27/28 patients. PTK 1) did not   lead to complications (one corneal perforation in control group), 2) accelerated corneal epithelialization on 18,4 days compared   to surgical keratectomy group (p = 0.000, Kruskal-Wallis test), 3) improved mean visual acuity on 0.08 compared to control   group in 6 months follow-up examination (Bonferroni corrected p = 0.002, Kruskal-Wallis test).  Conclusion: PTK is a safe and effective method for treatment of post-burn superficial persistent corneal ulcers recalcitrant to   conventional therapy.",
author="Lakimenko, Stanislav
and Buznyk, Oleksiy
and Shchypun, Sergiy",
pages="195--200",
url="https://www.termedia.pl/Treatment-of-post-burn-persistent-corneal-r-nulcers-with-excimer-laser-phototherapeutic-r-nkeratectomy-Prospective-clinical-trial,124,48614,1,1.html"
}