@Article{Myśliwiec2007,
journal="Klinika Oczna / Acta Ophthalmologica Polonica",
issn="0023-2157",
volume="109",
number="2",
year="2007",
title="Ocena związku pomiędzy naczyniowym czynnikiem 
wzrostu śródbłonka (VEGF), czynnikiem martwicy 
nowotworu (TNF-α), interleukiną 6 (IL-6), 
wyrównaniem metabolicznym (HbA1c) a rozwojem 
retinopatii cukrzycowej u dzieci z cukrzycą typu 1.",
abstract="The aim of the work is to assess the correlation between HbA1c, VEGF, TNF-α, IL-6 and the development of diabetic retinopathy in children diagnosed with diabetes mellitus type 1. One hundred fourty nine children with long-standing diabetes mellitus type 1 were enrolled in the study. The patients were divided into two subgroups: children with retinopathy (Group 1; n=28) and children without retinopathy (Group 2, n=121). The control group consisted of 62 healthy children. All the examined children had VEGF, TNF-α and IL-6 measured in the blood serum using highly sensitive ELISA tests. Statistically significant higher blood serum levels of HbA1c, VEGF, TNF-α and IL-6 were found in the group 1 in comparison with the group 2. Children of the group 2 in relation to healthy controls showed statistically significant higher blood serum levels of VEGF, TNF-α and IL-6. Elevated levels of VEGF, TNF-α, IL-6, HbA1c in blood serum of children with diabetes mellitus type 1 detected before development of overt signs of diabetic retinopathy might indicate the possibility of the occurrence of changes in the eye shortly.",
author="Myśliwiec, Małgorzata
and Balcerska, Anna
and Zorena, Katarzyna
and Myśliwska, Jolanta
and Lipowski, Paweł
and Raczyńska, Krystyna",
pages="150--154",
url="https://www.termedia.pl/The-assessment-of-the-correlation-between-vascular-endothelial-r-ngrowth-factor-VEGF-tumor-necrosis-factor-TNF-interleukin-6-IL-6-r-nglycaemic-control-HbA1c-and-the-development-of-the-diabetic-r-nreti,124,49562,1,1.html"
}