@Article{Postępska2024,
journal="Pediatria Polska - Polish Journal of Paediatrics",
issn="0031-3939",
volume="99",
number="4",
year="2024",
title="Application of bone turnover markers in skeletal 
and extra-skeletal conditions in children and adults",
abstract="The assessment of bone health is challenging. It comprises bone histomorphometry, imaging techniques and laboratory parameters including bone turnover markers (BTMs). The latter are bone-derived products which can be measured in biological fluids, including blood and urine. Considering the disadvantages and limitations of imaging techniques, BTMs serve as an additional, non-invasive source of information about the metabolic activity of the entire skeleton. BTMs have found applications as research and clinical tools in a wide range of skeletal and extra-skeletal conditions, including diagnosis and treatment of osteoporosis. Unfortunately, their utility in routine clinical practice, especially in children, is still limited due to heterogenous methodo­logy, intra- and inter patient variability, and a paucity of accurate reference ranges and approved guidelines. Therefore, there is a need for standardized clinical trials on currently available and new BTMs.",
author="Postępska, Agnieszka
and Sikora, Przemysław",
pages="319--328",
doi="10.5114/polp.2024.145804",
url="http://dx.doi.org/10.5114/polp.2024.145804"
}