@Article{Wiland2006,
journal="Reumatologia/Rheumatology",
issn="0034-6233",
volume="44",
number="3",
year="2006",
title="Review PaperB cell depletion with monoclonal antibody as treatment for rheumatoid arthritis",
abstract="In recent years our knowledge of the role of B lymphocytes in the pathogenesis of rheumatoid arthritis (RA) has expanded and it is now thought that B cells have a more extensive role than was previously appreciated. They seem to play a pivotal role in the activation of synovial T cells and induction of cytokine secretion. CD20 antigen expressed on the surface of B cells is highly specific to B cells. The success of B cell depletion therapy by using the monoclonal antibody Rituximab, which targets CD20, further emphasized the importance of B cells in the pathogenesis of RA.",
author="Wiland, Piotr",
pages="162--168",
url="https://www.termedia.pl/Review-Paper-B-cell-depletion-with-monoclonal-antibody-as-treatment-for-rheumatoid-arthritis,18,6240,1,1.html"
}