@Article{Bernacki2000,
journal="Contemporary Oncology/Współczesna Onkologia",
issn="1428-2526",
volume="4",
number="2",
year="2000",
title="Neoadjuvant radiochemotherapy in squamous cell cancer 	of the esophagus \– morphological assessment and clinical results",
abstract="The study was perfomed in 37 pateints with squamous cell carcinoma of the esophagus in two groups. In group I \– 12 patients received no preoperative treatment, in group II \– in 25 patients preoperative concurrent radiotherapy (200 cGy/day to tatal dose of 3000 cGy) and chemotherapy (Cisplatin \– on days 1 to 5 and 17 to 21 at a dose of 20 mg/m 2 /day and 5-Fluorouracyl continuous i. v. infusion of 300 mg/m 2 /day) were administered. In group II after operation in 4 patients microscopic examination revealed no presence of cancer cells \– complete response (CR). Of twelve patients with reduction of neoplastic infiltration 7 had partial response 1 (PR1) and 5 had partial response 2 (PR2). In 7 patients no changes were detected \– stable disease (SD). In clinical examination we assessed \– stage of the disease (pTNM), postoperative complications and 2-years survival. 27% of the patients in group I and 48% of patients in group II survived 2 years after the operation.   Conclusions: Neoadjuvant radiochemotherapy improves 2-years survival rate in squamous cell esophageal cancer. Long term clinical results correlate with the response of the tumour to the preoperative treatment.",
author="Bernacki, Andrzej
and Nikliński, Jacek
and Laudański, Jerzy
and Furman, Krzysztof
and Furman, Marian
and Kozłowski, Mirosław
and Kiluk, Stanisław",
pages="58--60",
url="https://www.termedia.pl/Neoadjuvant-radiochemotherapy-in-squamous-cell-cancer-of-the-esophagus-8211-morphological-assessment-and-clinical-results,3,656,1,1.html"
}