@Article{Krzysiek2006,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="5",
number="4",
year="2006",
title="Influence of six months\’ transdermal 17\β -oestradiol administration combined with oral medroxyprogesterone or oral simvastatin treatment on glycaemia and insulinaemia  in postmenopausal women with normal and impaired glucose tolerance",
abstract="  Aim of study:  Comparison between influence of transdermal continuous 17\β-oestradiol combined with oral medroxyprogesterone (HRT) and oral simvastatin treatment on glycaemia and insulinaemia in postmenopausal women with normal and impaired glucose tolerance.   Materials and methods:  68 postmenopausal women were allocated to six groups. Groups A, B and C consisted of women with normal glucose tolerance, while groups D, E and F had women with impaired glucose tolerance. Group A 17 patients, group D 11 patients. Both groups received HRT. Groups B (10 women) and E (10 women) received simvastatin 20 mg orally. Groups C (10 women) and F (10 women) were controls.    Results:  Basic fasting FSH, oestradiol, DHEAS, SHBG insulin and plasma levels were assessed as well as glucose and insulin during OGTT. HRT increased plasma insulin levels in women with normal glucose tolerance and had no such effect in women with IGT. Simvastatin had no effect on plasma insulin and glucose levels in postmenopausal women with normal glucose tolerance and reduced fasting insulin level in women with IGT.",
author="Krzysiek, Józef
and Milewicz, Tomasz
and Sztefko, Krystyna
and Skucińska, Dorota
and Radowicki, Stanisław",
pages="204--212",
url="https://www.termedia.pl/Influence-of-six-months-8217-transdermal-17-946-oestradiol-administration-combined-with-oral-medroxyprogesterone-or-oral-simvastatin-treatment-on-glycaemia-and-insulinaemia-in-postmenopausal-women-wit,4,6692,1,1.html"
}