@Article{Wolska-Kuśnierz2005,
journal="Central European Journal of\ Immunology",
issn="1426-3912",
volume="30",
number="3",
year="2005",
title="Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children\’s Memorial Health Institute, Warsaw",
abstract="Nine hundred and forty-six cases of primary immunodeficiency diseases were diagnosed in the Department of Immunology of the Children\’s Memorial Health Institute in Warsaw during 1980-2006. The highest frequency was that of antibody immunodeficiencies: 547 (57.8%). Predominantly T cell deficiencies were recognised in 80 (8.5%) children. In 29 children severe combined immunodeficiencies with different genetic defects were diagnosed, and in 18 of them hematopoietic stem cell transplantation was done. In the group of phagocytic disorders (95; 10% of patients), neutropenia was the most common - 46 cases, followed by chronic granulomatous diseased recognised in 41 patients. In the group of other well-defined PIDs - immunodeficiencies associated with chromosomal instability were the most common (152; 16% of patients). Ataxia \– teleangiectasia was diagnosed in 92 cases and, next, Nijmegen Breakage syndrome in 57 children. Hyper IgE syndrome was diagnosed in 22 patients, and Wiskott-Aldrich syndrome in 19 boys.",
author="Wolska-Kuśnierz, Beata
and Pac, Małgorzata
and Pietrucha, Barbara
and Heropolitańska-Pliszka, Edyta
and Klaudel-Dreszler, Maja
and Kurenko-Deptuch, Magdalena
and Gregorek, Hanna
and Michałkiewicz, Jacek
and Piątosa, Barbara
and Bernatowska, Ewa",
pages="3--4",
url="https://www.termedia.pl/Twenty-five-years-of-investigations-into-primary-immunodeficiency-diseases-in-the-Department-of-Immunology-The-Children-8217-s-Memorial-Health-Institute-Warsaw,10,6799,1,1.html"
}