@Article{Peruga2006,
journal="Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej",
issn="1734-9338",
volume="2",
number="3",
year="2006",
title="Original papersLong-term follow-up of rapamycin-eluting stent implantation in patients with coronary  artery disease",
abstract="Restenosis remains the major limitation of percutanoues coronary interventions (PCI). Widespread use of conventional intracoronary stents has lowered its frequency. However, repeat narrowing of a coronary artery can still affect 10% to 30% of patients post PCI.   Objective:  The aim of the study was to assess the efficacy of rapamycin-eluting stent (DES) implantation in patients at highest risk of restenosis in case of conventional bare-metal stent implantation.   Results:  Rapamycin-eluting stent implantation was performed in 286 patients, including 8 patients (2.8%) with acute myocardial infarction and 98 (34.2%) patients with unstable angina. Restenosis post previous PCI was the indication for DES implantation in 80.4% of patients. The procedure was successful in all patients. During the average 28.7-month follow-up 6 deaths occurred, including 4 (1.4%) probably coronary-related deaths, and in 8 patients acute myocardial infarction was diagnosed. In 59 (20.6%) patients control coronary angiography was performed 6-9 months after the procedure. In-stent restenosis was diagnosed in one (0.4%) patient and in 18 patients restenosis within 5 mm of either pole of DES was seen. No cases of stent thrombosis were revealed.   Conclusions:  In patients with coronary artery disease at highest risk of restenosis in case of conventional bare-metal stent implantation, drug-eluting stents significantly reduce restenosis rate and the need for repeated PCI, thus improving the outcome of percutaneous treatment of coronary artery disease.",
author="Peruga, Jan
and Kasprzak, Jarosław D.
and Kopff, Anna
and Kidawa, Michał
and Plewka, Michał
and Krzemińska-Pakuła, Maria",
pages="214--218",
url="https://www.termedia.pl/Original-papers-Long-term-follow-up-of-rapamycin-eluting-stent-implantation-in-patients-with-coronary-artery-disease,35,6879,1,1.html"
}