@Article{Znojek2007,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="6",
number="2",
year="2007",
title="Analysis of risk factors for endometrial neoplasia as a method for supplementation of indications for D\&C in postmenopausal women with uterine bleeding",
abstract="  Objectives: A diagnostic dilemma exists regarding whether D\&C is an obligatory procedure during every hospitalization caused by recurrent uterine bleeding. The decision could be supported by consideration of risk factors obtained from patient\&#8217;s medical history and clinical examination.  Design: The aim of the study was to answer whether analysis of risk factors for endometrial neoplasia could supplement indications for D\&C in a group of postmenopausal women with uterine bleeding.    Materials and methods:  The study group consisted of n=154 postmenopausal women hospitalized between 2000 and 2004 in the Gynaecology Dept. of 5th WSKP in Cracow, and subjected to D\&C because of uterine bleeding. Retrospective analysis of data extracted from medical charts and pathological examination was based on Pearson\&#8217;s linear correlation, linear regression, OR and ROC analysis as well as logistic regression model.    Results:  Logistic regression revealed that the most important risk factors for endometrial neoplasia were: weight \&#8805;70 kg (OR=3.9), positive history of hypertension (OR=2.0), values of diastolic blood pressure \&#8805;85 mmHg (OR=3.2), age of menopause \&#8805;52 years (OR=2.6), age \&#8805;60 years (OR=2.3) and no HT use (OR=2.0). The chance for endometrial neoplasia combined for all risk factors was OR=5.34 (p<0.0005).    Conclusion:  Analysis of risk factors indicates patients with the greatest probability of endometrial neoplasia and influences the more accurate targeting of D\&C procedure to postmenopausal women with uterine bleeding.",
author="Znojek, Wojciech
and Wilczyński, Jacek R.
and Hille, Grzegorz",
pages="110--114",
url="https://www.termedia.pl/Analysis-of-risk-factors-for-endometrial-neoplasia-as-a-method-for-supplementation-of-indications-for-D-C-in-postmenopausal-women-with-uterine-bleeding,4,8107,1,1.html"
}