@Article{Laskowska1999,
journal="Contemporary Oncology/Współczesna Onkologia",
issn="1428-2526",
volume="3",
number="6",
year="1999",
title="Structure and function of mucins, their role in tumor progression",
abstract="Mucin-type glycoproteins are produced by epithelial cells of gastrointestinal, respiratory and urogenital tracts as secreted or membrane-bound molecules. Their protein backbone is charakterized by the presence of repeating sequences rich in serine, threonine and proline residues. Mucins are highly glucosylated glycoproteins containing numerous O-linked oligosaccharides, often terminated in silic acid. The increasing number of evidence suggest that because of their extended, filamentous structures, negative charge, presence of specific carbohydrate structures they play a role in mucosal defence, cellular signalling and cell-cell interactions. Mucins undergo characteristic changes in their expression associated with neoplastic transformation. They are the carries of tumor-associated antigens, and probably one of the factors promoting metastasis.",
author="Laskowska, Anna
and Ugorski, Maciej",
pages="244--248",
url="https://www.termedia.pl/Structure-and-function-of-mucins-their-role-in-tumor-progression,3,812,1,1.html"
}