@Article{Hauser2007,
journal="Neuropsychiatria i Neuropsychologia/Neuropsychiatry and Neuropsychology",
issn="1896-6764",
volume="2",
number="1",
year="2007",
title="Review articleFamiliality of clinical features in bipolar affective disorder: implications for molecular genetic studies",
abstract="Epidemiological studies suggest that individual variation in susceptibility to bipolar affective disorder (BP) is largely genetic, reflecting alleles of moderate effect in multiple genes. Molecular genetic studies have identified several potential regions of linkage, but specific genes that contribute to the illness remain unclear. Progress in identifying the genetic basis of bipolar affective disorder has been disappointing probably because of genetic and phenotypic heterogeneity of this illness. It is highly likely that using alternative phenotypes instead of only DSM and ICD diagnostic criteria will lead more rapid success in the search for susceptibility genes. BP is clinically heterogeneous, and clinical features that run in families may help define more homogeneous phenotypes. The objective of this paper is to describe clinical phenotypes that can be employed in psychiatric genetic studies of BP. Linkage and association studies are summarized in reference to subtypes of BP.",
author="Hauser, Joanna",
pages="37--45",
url="https://www.termedia.pl/Review-article-Familiality-of-clinical-features-in-bipolar-affective-disorder-implications-for-molecular-genetic-studies,46,8684,1,1.html"
}