%0 Journal Article %J Medycyna Paliatywna/Palliative Medicine %@ 2081-0016 %V 3 %N 1 %D 2011 %F Gottwald2011 %T Bone metastases from breast cancer – analysis of 63 cases %X Objectives : Breast cancer is the most common malignant neoplasm in women. In metastatic disease bones are often involved. The aim of the study : was to investigate the clinical feature in patients with breast cancer metastasized to bones. Material and methods : Sixty-three patients were studied retrospectively. Clinical and pathologic data were analyzed. The time from primary diagnosis until the relapse in bones was evaluated. Metastatic tumors in bones were characterized. Results : At the diagnosis of primary cancer the patients aged 34-70 years old (54.0 ±8.7). The histology of the cancer was ductal adenocarcinoma (85.7%) and lobular adenocarcinoma (14.3%). The interval from diagnosis of primary cancer until the relapse in bones was 0-216 months (52.1 ±60.5). Bone metastases were less often solitary (25.4%) than multifocal (74.6%). In 47.6% metastatic tumors were diagnosed only in bones, and 52.4% of patients had additional metastases. The synchronous metastases were located most commonly in central nervous system, liver and lungs. The treatment of relapse in bones was in 6.4% surgery followed by radiotherapy, in 73% of patients radiotherapy alone and in 20.6% only palliative care. Conclusions : The development of brain metastases occurs commonly in patients aged over 60 years old. Bone metastases are in most cases multifocal, and in near 50% of patients synchronous extra­osseous metastases develop. The oncologic treatment of choice in bone metastases from breast cancer remain palliative radiotherapy. %A Gottwald, Leszek %A Kaźmierczak-Łukaszewicz, Sylwia %A Dukowicz, Andrzej %A Misiewicz, Piotr %A Ciałkowska-Rysz, Aleksandra %P 39-43 %9 journal article %U https://www.termedia.pl/-Bone-metastases-from-breast-cancer-analysis-of-63-cases-,59,16529,1,1.html