%0 Journal Article %J Polish Journal of Pathology %@ 1233-9687 %V 63 %N 2 %D 2012 %F Skotnicki2012 %T Invasive lobular carcinoma of the breast: cytometric and immunohistochemical characteristics of 96 cases %X The aim of the study was to present microscopic, cytometric and immunohistochemical characteristics of a group of 96 invasive lobular carcinomas (ILC) of the breast. Ninety six patients treated surgically at the Department of Surgical Oncology, Centre of Oncology – Maria Skłodowska-Curie Memorial Institute, Cracow Branch, between 1983 and 1996, were included into the study. In 56 (58.3%) cases, a classical pattern of ILC was diagnosed, whereas atypical variants (solid, pleomorphic, pleomorphic with signet ring cells, signet ring cell, and tubulolobular) were recognized in 40 (41.7%) cases. ILC was characterized by lack of E-cadherin expression, high rate of steroid receptor expression, low rate of P53 and c-erb-B2 expressing tumours, low MIB-1 labelling index, and low S phase fraction, as well as high rate of diploid lesions. %A Skotnicki, Piotr %A Ryś, Janusz %A Blecharz, Paweł %A Reinfuss, Marian %A Jakubowicz, Jerzy %A Ambicka, Aleksandra %A Kruczak, Anna %A Lackowska, Bożena %P 112-120 %9 journal article %U https://www.termedia.pl/Invasive-lobular-carcinoma-of-the-breast-cytometric-and-immunohistochemical-characteristics-of-96-cases,55,19061,1,1.html