%0 Journal Article %J Gastroenterology Review/Przegląd Gastroenterologiczny %@ 1895-5770 %V 7 %N 6 %D 2012 %F Gąsiorowska2012 %T Evaluation of pH-impedance testing in diagnosis of patients with suspected extra-oesophageal manifestations of gastroesophageal reflux disease %X Introduction: Combined multichannel intraluminal impedance and pH-metry (MII-pH) is a technique that enables monitoring of gastroesophageal reflux disease (GERD) independently of its acidity. Aim : To investigate the utility of MII-pH testing among patients with suspected GERD with atypical symptoms. Material and methods: Thirty-two consecutive patients underwent gastroscopy and MII-pH testing to evaluate the cause of atypical symptoms presumed due to GERD. Among them, 19 patients with unexplained chronic cough, sore throat, globus and hoarse voice were included in group 1 – laryngological symptoms. Videolaryngoscopic examination was used to document reflux-related laryngitis. Group 2 – miscellaneous symptoms – included 13 patients with nausea, chronic burning in the mouth and throat, belching, dyspnoea, wheezing and upper abdominal discomfort. Results: In group 1, with laryngological symptoms, 32%, 16%, and 16% of patients were found to have symptoms of acid reflux, non-acid reflux or both, respectively. Eight patients (42%), who did not show any changes in videolaryngoscopy, had MII-pH documented acid reflux. Application of MII-pH allowed the relation between laryngeal symptoms and acid reflux to be confirmed in 1/3 of all examined patients. In group 2, with miscellaneous symptoms, acid reflux was found in 3 patients (23%) and non-acid GER in 2 patients (15%). The majority of patients (62%) from the group with miscellaneous symptoms did not have GER. Conclusions : MII-pH testing is useful in determining whether gastroesophageal reflux occurs in patients with atypical symptoms. MII-pH testing was useful in redirecting the management of patients who did not have reflux as the cause of their symptoms. %A Gąsiorowska, Anita %A Talar-Wojnarowska, Renata %A Łapienis, Magdalena %A Schmidt, Jacek %A Czupryniak, Leszek %A Małecka-Panas, Ewa %P 386-396 %9 journal article %R 10.5114/pg.2012.33049 %U http://dx.doi.org/10.5114/pg.2012.33049