%0 Journal Article %J Pediatric Endocrinology Diabetes and Metabolism %@ 2081-237X %V 28 %N 1 %D 2022 %F Dekker2022 %T Which C-peptide assay do you use? Increasing need for describing C-peptide assay performance %X Many C-peptide assays are commercially available for research and routine use. However, not all assays yield consistent results, especially in the low concentration ranges. We searched the literature describing C-peptide measurements to assess which assays are mainly used in the diabetes research field and if they are specified. Percentages of publications on C-peptide measurements in type 1 diabetes (T1D), type 2 diabetes (T2D) and other forms of diabetes were 32%, 54% and 14%, respectively. In only 54% of the publications the used assay was specified. Information on detection limit, measurement range and variation was provided in 12%, 2% and 11% of publications, respectively. In 22% of all publications no C-peptides concentrations were mentioned. This may be a problem especially for T1D research, where measuring very low levels of C-peptide is becoming increasingly important and concordance between assays is low. %A Dekker, Pim %A de Vries, Martine %A Aanstoot, Henk-Jan %A Groen, Joost %P 101-103 %9 journal article %R 10.5114/pedm.2022.113741 %U http://dx.doi.org/10.5114/pedm.2022.113741