TY - JOUR JO - Polish Journal of Pathology SN - 1233-9687 VL - 63 IS - 1 PY - 2012 ID - Pietkiewicz2012 TI - Pemphigoid gestationis in a female with progressive facial hemiatrophy: microchimerism as a speculative shared background is disputable AB - The commonest source of naturally acquired microchimerism, i.e. small numbers of foreign cells within the organism, is two-way mother-fetus transplacental trafficking during pregnancy. Here, the first report on coexistence of pregnancy-associated pemphigoid gestationis (PG) and progressive facial hemiatrophy, a form of “ en coup de sabre ” morphea, is presented. HE histopathology (eosinophil-rich subepidermal infiltration, inverted teardrop sign), direct immunofluorescence (linear IgG1, but not IgG4, deposits along the dermal-epidermal junction) and ELISA (elevated levels of serum and blister fluid IgG autoantibodies to BP180) corroborated the PG diagnosis. Microchimerism as a speculative shared background of those two rare autoimmune diseases is disputable. AU - Pietkiewicz, Paweł AU - Gornowicz-Porowska, Justyna AU - Bowszyc-Dmochowska, Monika AU - Dmochowski, Marian SP - 71 EP - 74 DA - 2012 UR - https://www.termedia.pl/Pemphigoid-gestationis-in-a-female-with-progressive-facial-hemiatrophy-microchimerism-as-a-speculative-shared-background-is-disputable,55,18486,1,1.html ER -