TY - JOUR JO - Reumatologia/Rheumatology SN - 0034-6233 VL - 53 IS - 3 PY - 2015 ID - Bielewicz-Zielińska2015 TI - Case reportsUnusual location of tuberculosis in the course of tumor necrosis factor α inhibitor therapy AB - Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis complex mycobacteria. Extrapulmonary tuberculosis usually develops more than two years after infection or many years later. Factors favoring onset of the disease are malnutrition, older age, renal failure, diabetes, cancer, immunosuppression and biological treatment, e.g. tumor necrosis factor α (TNF-α) inhibitors. The paper presents a case of a 56-year-old patient with ankylosing spondylitis treated with infliximab, diagnosed with tuberculosis of the spleen. The unusual location and uncharacteristic symptoms created a lot of diagnostic difficulties, particularly as during qualification for biological treatment tests are performed to exclude infection with Mycobacterium tuberculosis . Pharmacological treatment of tuberculosis is typical, but in the case of tuberculosis of the spleen, splenectomy also is a method of treatment. The decision was made to implement pharmacological treatment, which proved to be effective, so the patient avoided surgery. AU - Bielewicz-Zielińska, Agnieszka AU - Brzezicki, Jan AU - Rymko, Marcin AU - Jeka, Sławomir SP - 161 EP - 164 DA - 2015 DO - 10.5114/reum.2015.53139 UR - http://dx.doi.org/10.5114/reum.2015.53139 ER -