TY - JOUR JO - Archives of Medical Science SN - 1734-1922 VL - 13 IS - 1 PY - 2017 ID - Bartolo2017 TI - Infusional high-density lipoproteins therapies as a novel strategy for treating atherosclerosis AB - High-density lipoproteins (HDL) have received considerable interest as a target for the development of novel anti-atherosclerotic agents beyond conventional approaches to lipid lowering. While a number of approaches have focused on modifying remodeling and expression pathways implicated in the regulation of HDL levels, an additional approach involves simply infusions of delipidated HDL. Several groups have advanced HDL infusions to clinical development with intriguing signs suggesting potentially favorable impacts at the level of the artery wall. The findings of early studies of infusional HDL therapies will be reviewed. AU - Bartolo, Belinda A. Di AU - Schwarz, Nisha AU - Andrews, Jordan AU - Nicholls, Stephen J. SP - 210 EP - 214 DA - 2017 DO - 10.5114/aoms.2016.60941 UR - http://dx.doi.org/10.5114/aoms.2016.60941 ER -