TY - JOUR JO - Archives of Medical Science SN - 1734-1922 VL - 13 IS - 6 PY - 2017 ID - Talebreza2017 TI - Investigation of clinicopathological parameters in emergency colorectal cancer surgery: a study of 67 patients AB - Introduction: The aim of the present study was to establish, having adjusted for case mix, the size of the differences in postoperative mortality and 5-year survival between patients presenting as an emergency with evidence of obstruction and perforation and the association of clinicopathological factors with mortality (bivariate analyses). Material and methods : The study included 67 patients who presented with colorectal cancer (CRC) between 2009 and 2013 in Iran. The mean age of the patients was 59.7 years. Of the 67 patients, 37 (55.22%) were male and 30 (44.77%) were female. Certain parameters that correlated with CRC and surgical treatment were investigated Results: Our results showed that 46 (68.65%) patients had obstruction, while perforation was observed in 21 (31.34%) cases. Among the patients with obstruction, obstruction of the right colon was observed in 29 (43.28%) cases. There was no significant difference in mortality rate between right and left colonic obstruction. Based on the bivariate analyses, our findings showed that death of patients was significantly related to tumor grade (p = 0.02) and TNM staging (p = 0.026), but no association was found between other parameters and death, including age, sex, and tumor site. Conclusions : Compared with patients who undergo elective surgery for colon cancer, those who present as an emergency with evidence of obstruction or perforation have higher postoperative mortality rates and poorer cancer-specific survival. Also, colorectal cancer patients with emergency surgery showed aggressive histopathology and an advanced stage. AU - Talebreza, Amir AU - Yahaghi, Emad AU - Bolvardi, Ehsan AU - Masoumi, Babak AU - Bahramian, Mehran AU - Darian, Ebrahim Khodaverdi AU - Ahmadi, Koorosh SP - 1394 EP - 1398 DA - 2017 DO - 10.5114/aoms.2016.61385 UR - http://dx.doi.org/10.5114/aoms.2016.61385 ER -