TY - JOUR JO - Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej SN - 1734-9338 VL - 13 IS - 4 PY - 2017 ID - Zbroński2017 TI - Patient-prosthesis mismatch in patients treated with transcatheter aortic valve implantation – predictors, incidence and impact on clinical efficacy. A preliminary study AB - Introduction : Patient-prosthesis mismatch (PPM) is relatively frequent after surgical aortic valve replacement (SAVR) and negatively impacts prognosis. Aim : We sought to determine the frequency and clinical effects of PPM after transcatheter aortic valve implantation (TAVI). Material and methods : Overall, 238 patients who underwent TAVI were screened. Moderate PPM was defined as indexed effective orifice area (EOAi) between 0.65 and 0.85 cm2/m2, and severe PPM as < 0.65 cm2/m2. All-cause mortality and the Valve Academic Research Consortium 2 (VARC-2) defined composite of clinical efficacy at 1 year were the primary endpoints. Results : Finally, 201 patients were included (mean age: 79.6 ±7.4 years, 52% females). The femoral artery served as the delivery route in 79% and most of the prostheses were self-expanding (68%). Any PPM was present in 48 (24%) subjects, and only 7 (3.5%) had severe PPM. Body surface area (BSA) independently predicted any PPM (OR = 16.9, p 20 mm Hg. Conclusions : Severe PPM after TAVI is rare, can be predicted by larger BSA and does not seem to affect mid-term mortality or composite clinical outcome. Larger studies are needed to find different independent predictors of PPM and elucidate its impact in terms of device durability and long-term clinical efficacy. AU - Zbroński, Karol AU - Rymuza, Bartosz AU - Scisło, Piotr AU - Grodecki, Kajetan AU - Dobkowska, Paulina AU - Wawrzacz, Marek AU - Wilimski, Radosław AU - Słowikowska, Anna AU - Kochman, Janusz AU - Filipiak, Krzysztof J. AU - Opolski, Grzegorz AU - Huczek, Zenon SP - 281 EP - 287 DA - 2017 DO - 10.5114/aic.2017.71608 UR - http://dx.doi.org/10.5114/aic.2017.71608 ER -