TY - JOUR JO - Archives of Medical Science SN - 1734-1922 VL - 15 IS - 2 PY - 2019 ID - Dai2019 TI - Associations of dipping and non-dipping hypertension with cardiovascular diseases in patients with dyslipidemia AB - Introduction : Dyslipidemia combined with hypertension increases the risk of cardiovascular disease (CVD). The current study aimed to investigate the association of dipping and non-dipping hypertension with CVD in patients with dyslipidemia. Material and methods : A total of 243 documented dyslipidemia patients with hypertension were enrolled. Clinical characteristics and clinic and 24-hour blood pressure (BP) parameters were compared between dipping and non-dipping groups based on 24-hour ambulatory blood pressure monitoring. Logistic regression analysis was performed to evaluate the association of dipping and non-dipping hypertension with CVD. Results : Compared to the dipping group, patients in the non-dipping group were older, more likely to be male and smokers, had higher serum creatinine levels, and were more likely to have chronic kidney disease and CVD (p < 0.05 for all comparisons). No significant between-group differences in clinic systolic and diastolic BP (SBP and DBP) were observed. However, compared to the dipping group, 24-hour SBP, nighttime SBP and DBP, and night-day ratio of SBP and DBP were all significantly higher in the non-dipping group (p < 0.05 for all comparisons). In the dipping group, only night-day ratio of SBP was significantly associated with CVD, with an odds ratio (OR) of 1.09 (95% confidence interval (CI) of 1.02–1.34). In the non-dipping group, both night-day ratio of SBP and DBP were significantly associated with CVD, with an OR of 1.72 (95% CI: 1.33–2.06) and 1.23 (95% CI: 1.05–1.66), respectively. Conclusions : In patients with dyslipidemia, non-dipping hypertension is more closely related to CVD compared to dipping hypertension. AU - Dai, Siping AU - Huang, Bo AU - Zou, Yunliang AU - Liu, Yan SP - 337 EP - 342 DA - 2019 DO - 10.5114/aoms.2018.72609 UR - http://dx.doi.org/10.5114/aoms.2018.72609 ER -