TY - JOUR JO - Reumatologia/Rheumatology SN - 0034-6233 VL - 55 IS - 6 PY - 2017 ID - Kundak2017 TI - A child with subcorneal pustular dermatosis responded to IVIG treatment (Sneddon-Wilkinson disease) AB - Subcorneal pustular dermatosis (SPD) is a rare, chronic, recurrent dermatosis characterised by sterile pustules. It develops mainly in middle-aged or elder women, but is also rarely seen in children. The exact aetiology of the disease is unknown. In literature, cases associated with IgA gammopathy have been reported. In this article; we report a case of a five-year-old girl who was diagnosed as SPD by clinical features, histopathological characteristics, and direct immunofluorescence analysis results. IgA was high, and IgG-IgM and CD19+ B cell were low. We noticed that during IVIG treatment for immunodeficiency, dermatological symptoms were recovered rapidly. Clinical profile of SPD and its association with systemic diseases may provide early detection of immune dysfunction. AU - Kundak, Selcen AU - Bağ, Özlem AU - Gülez, Nesrin AU - Ergin, Malik SP - 323 EP - 327 DA - 2017 DO - 10.5114/reum.2017.72631 UR - http://dx.doi.org/10.5114/reum.2017.72631 ER -