TY - JOUR JO - Central European Journal of Immunology SN - 1426-3912 VL - 47 IS - 1 PY - 2022 ID - Miłosz2022 TI - Validation of the test for detecting SARS--CoV-2 antigens in the Polish population in patients with suspected SARS-CoV-2 infection AB - In December 2019, the World Health Organization (WHO) reported that China had accumulated pneumonia of unclear etiology in Wuhan. According to WHO recommendations, in strictly defined situations, antigen tests can be implemented into the diagnostic algorithm to reduce the number of molecular tests performed and support the rapid identification and treatment of COVID-19 patients. According to WHO recommendations, the antigen test for diagnostic use should have a sensitivity of ≥ 80% and a specificity of ≥ 97% compared to molecular tests (NAAT). Based on the comparative analysis, the sensitivity and specificity of the SARS-CoV-2 Antigen ELISA test were determined concerning the RT-PCR reference method. The sensitivity of the SARS-CoV-2 Antigen ELISA was 100% (51/51) and the specificity was 98.84%. The obtained data demonstrate that the analyzed antigen test meets both the WHO and the Ministry of Health criteria. AU - Miłosz, Mateusz AU - Słota, Michał AU - Jakubowski, Jakub AU - Kwiatkowski, Piotr AU - Kasperczyk, Sławomir AU - Kozłowska, Małgorzata AU - Pawłowska, Barbara AU - Matuszek, Patryk AU - Kuta, Ewa SP - 58 EP - 62 DA - 2022 DO - 10.5114/ceji.2022.113992 UR - http://dx.doi.org/10.5114/ceji.2022.113992 ER -