Cardiometabolic risk factors in Turner syndrome

Aneta Gawlik; Joanna Gieburowska; Ewa Małecka-Tendera

eISSN: 2083-8441
ISSN: 2081-237X

Pediatric Endocrinology Diabetes and Metabolism

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abstract:

Review paper

Cardiometabolic risk factors in Turner syndrome

Aneta Gawlik

,

Joanna Gieburowska

,

Ewa Małecka-Tendera

Pediatr Endocrino Diabetes Metab 2014;20,2:69-74

Online publish date: 2015/07/31

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Congenital cardiovascular structural abnormalities, hypertension, low birth weight, increased prevalence of obesity, frequent glucose intolerance and dyslipidemia are risk factors of premature mortality for cardiovascular events in Turner syndrome (TS). The life expectancy in TS is reduced by at least 10 years and the risk of premature death is increased 3-fold compared to general female population. Hormonal therapy in TS, both estrogens in different algorithms and growth hormone in supraphysiological dose, may additionally modify these factors. In this review we summarize cardiometabolic markers potentially present in girls and women with TS.

keywords:

Cardiometabolic risk factors in Turner syndrome

Aneta Gawlik , Joanna Gieburowska , Ewa Małecka-Tendera

Turner syndrome, metabolic syndrome, cardiometabolic risk factors

Aneta Gawlik

,

Joanna Gieburowska

,

Ewa Małecka-Tendera